Influencing Factors of Mortality Among Adult HIV Patients Under Antiretroviral Therapy: The Case of Hossana Queen Elleni Mohammad Memorial Hospital, Ethiopia
Gizachew Gobebo,
Alemayehu Siffir,
Belema Hailu,
Birhanu Woldeyohannes,
Bizunesh Kefale,
Temesgen Senbeto,
Adinew Handiso,
O. Chandrasekhara Reddy
Issue:
Volume 10, Issue 3, September 2021
Pages:
72-77
Received:
31 July 2021
Accepted:
16 August 2021
Published:
24 August 2021
Abstract: Even though the use of ART has brought a significant reduction in the mortality and morbidity of patients living with HIV/AIDS globally, still a number of patients die after the start of Antiretroviral Therapy. This study aimed at identifying influencing factors of mortality among adult HIV infected patients who are on ART in Hossana Queen Elleni Mohammad Memorial Hospital. The data for the study were obtained from Hossana Queen Elleni Mohammad Memorial Hospital Antiretroviral Therapy clinic. The HIV infected patients ≥ 15 years of age. Binary logistic regression model was applied to analyze the data so as to identify the influencing factors associated with mortality of HIV infected patients. A total of 400 adult HIV infected patients who were under ART were included in the study. Of 400 patients, 18.75% of them died. Age of the patients 40 or above (OR=1.73, 95% CI: 1.13–1.92), primary education (OR=0.29, 95% CI: 0.030–0.71), secondary or above education (OR=0.13, 95% CI: 0.03–0.16), alcohol (OR=3.35, 95% CI: 1.79– 6.27), baseline weight 50 kg or above (OR=0.42, 95% CI: 0.23–0.77), TB positive (OR=3.76, 95% CI: 2.06–6.83), and baseline CD4 200 or above (OR=0.24, 95% CI: 0.19–0.50) were significantly associated with mortality among HIV patients under Antiretroviral Therapy. Health workers need to support those patients with no or little education by continuous awareness creation of taking care of themselves and knowing what factors facilitate death. Furthermore, patients who drink alcohol need to reduce excessive drinking.
Abstract: Even though the use of ART has brought a significant reduction in the mortality and morbidity of patients living with HIV/AIDS globally, still a number of patients die after the start of Antiretroviral Therapy. This study aimed at identifying influencing factors of mortality among adult HIV infected patients who are on ART in Hossana Queen Elleni M...
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Effect of High Volume Hemodiafiltration on Secondary Hyperparathyroidism Among Hemodialysis Patients
Ezzat Abdalrahman El Etreby,
Mohamed Said El-Shorbagy,
Al-Sayed Mohamed Rashed,
Ahmed Mohamed Alsawy
Issue:
Volume 10, Issue 3, September 2021
Pages:
78-84
Received:
14 May 2021
Accepted:
12 July 2021
Published:
28 October 2021
Abstract: Background: Despite increasing knowledge of the uraemic syndrome, both morbidity and mortality remain unacceptably high in patients with chronic kidney disease. Aim of the work: investigate the differences between conventional hemodialysis and hemodiafiltration in the context of chronic kidney disease metabolic bone disease findings serum calcium (sCa), phosphate (sPO4) and intact parathyroid hormone (PTHint) concentrations. Patients and methods: This prospective cross over study was approved by Almaadi hospital committee and included 95 patients with CKD5 on regular hemodialysis for at least 6 months. Patients were divided into two groups: Group A: 60 patients scheduled 6 months conventional high flux (hf-HD) (Period1) followed by 6 months of post-dilutional–HDF (Period2). Group B: (controls) included 35 patients were kept on conventional hf-HD for 12 months. (Period3) for 1st 6 months and (Period4) for 2nd 6 months. The main variables evaluated at the start as well as at the end of each period were sCa, sPO4 and PTHint. Results: There was highly significant statistical decrease in Phosphorus level in period2 compared to other groups after 2nd to 6th month and average of overall (p<0.001). A significant statistical decrease was found in Parathormone level and CRP in period2 compared to other groups after 1 month to 6th month and average of overall (p<0.05). There was significant statistical decrease in Albumin level in period2 compared to other groups after 2nd to 6th month and average of overall (p<0.05). There was a significant statistical increase in kt/v in period2 compared to other groups after 1st to 6th month and average of overall (p<0.05). Conclusion: The switch over from conventional Hf-HD to Ol-HDF results in a significant reduction of both PO4 and PTH concentrations, no significant changes in Ca concentrations.
Abstract: Background: Despite increasing knowledge of the uraemic syndrome, both morbidity and mortality remain unacceptably high in patients with chronic kidney disease. Aim of the work: investigate the differences between conventional hemodialysis and hemodiafiltration in the context of chronic kidney disease metabolic bone disease findings serum calcium (...
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