Volume 8, Issue 6, November 2019, Page: 66-71
Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center
Solonirina Davida Rakotomena, Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar
Sedera Arimino, Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar
Medyno Mampiadana Lovasoa, Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar
Tianarivelo Rajaonarivony, Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar
Hery Nirina Rakoto Ratsimba, Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar
Received: Dec. 4, 2019;       Accepted: Dec. 20, 2019;       Published: Jan. 4, 2020
DOI: 10.11648/j.sjcm.20190806.12      View  462      Downloads  192
Despite the introduction of H2 receptor and proton pump antagonists into the therapeutic arsenal of the Peptic Ulcer Disease, gastric perforation remains the most common surgical emergery for the upper gastrointestinal tract. The present study aims to describe the particularities of the management of Perforated Peptic Ulcer which underwent surgery in the University Hospital Center Joseph Ravoahangy Andrianavalona Antananarivo (CHU-JRA) and to identify its morbidity and mortality factors. This is a retrospective analysis performed over a period of 33 months from January 2017 to September 2019 on Perforated Peptic Ulcer operated in CHU-JRA. Demographic, clinical and therapeutic parameters were studied and analyzed in relation to the morbidity and mortality rate. Altogether 158 patients operated for perforated Gastric or Duodenal Ulcer were included with an age ranging from 16 to 78 years old, a mean age of 39.05±15.03 years and a Sex Ratio estimated to 18.75. Repeated unexplored epigastralgia was noted in 70.89% of cases and 33.54% of patients used NSAIDs and/or corticosteroids before the onset of the pain. At admission, 9.4% of cases were immediately in shock. A laparotomy for exploration and repair was performed for a suspicion of a hollow-organ perforation on a X-ray of an Unprepared Abdomen. Antral perforation predominated in our serie (75.95%) and the main repair procedure consisted in a simple surgical suture. To conclude, our stude reflects the difficulty of the management of Peptic Ulcer Disease and its complications in our daily practice. Strenghtening the awareness of the population about the potiential severity of this disease is essential.
Helicobacter pylori, Peptic Ulcer Disease, Perforation, Peritonitis, Surgery
To cite this article
Solonirina Davida Rakotomena, Sedera Arimino, Medyno Mampiadana Lovasoa, Tianarivelo Rajaonarivony, Hery Nirina Rakoto Ratsimba, Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center, Science Journal of Clinical Medicine. Vol. 8, No. 6, 2019, pp. 66-71. doi: 10.11648/j.sjcm.20190806.12
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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